Table 4.

Synergy and antagonism with fluoroquinolone combination therapy

Organism	Combination	Antagonism (%)	Indifferent (%)	Additive (%)	Synergy (%)
Staphylococcus aureus	Meropenem+ciprofloxacin	0	20	70	10
	Meropenem+moxifloxacin	0	60	40	0
	Moxifloxacin + teicoplanin	0	40	60	0
	Ciprofloxacin + teicoplanin	0	40	50	10
Pseudomonas aeruginosa	Meropenem+ciprofloxacin	0	10	80	10
	Meropenem+moxifloxacin	0	50	30	20
	Gentamicin +ciprofloxacin	10	13	6	0
	Gentamicin +moxifloxacin	0	80	0	20

In vitro results of a fluoroquinolone combined with a second antimicrobial against bacterial keratitis isolates. percentage of activity represents the percentage of isolates against which the respective antimicrobial combination provides a fractional inhibitory concentration that indicates an additive, indifferent, antagonistic or synergistic response.¹⁰⁵