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. 2022 Jul 16;10(20):6900–6914. doi: 10.12998/wjcc.v10.i20.6900

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Protein-protein interaction network. A: The protein-protein interaction (PPI) network of 115 overlapping genes of Sanqi and Huangjing and diabetes mellitus; B: Top 10 hub genes in the PPI network. AKT1: RAC-alpha serine/threonine-protein kinase; IL6: Interleukin 6; TNF: Tumor necrosis factor; TP53: Cellular tumor antigen p53; CASP3: Caspase-3; JUN: Transcription factor AP-1; MAPK1: Mitogen-activated protein kinase 1; MMP9: Matrix metallopeptidase-9; PTGS2: Prostaglandin G/H synthase 2; EGFR: Epidermal growth factor receptor.