Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 18;37(1):2004–2016. doi: 10.1080/14756366.2022.2100366

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Scheme 1. — Reagents and conditions: (a) KOH, (CH₃)₂SO₄, rt. for overnight; (b) CH₃CN, NBS, –10 °C, 12 h; (c) CH₃ONa, CuI, reflux for overnight; (d) POCl₃, DMF, reflux for 12 h; (e) CH₃MgI, Et₂O, NH₄Cl, rt for 20 h; (f) MnO₂, DCM, reflux for 12 h; (g) AlCl₃, CH₃CN, 60 °C for 3 h; (h) KOH in EtOH, reflux for 5 h.