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. 2022 Jul 17;44(1):1227–1235. doi: 10.1080/0886022X.2022.2100262

Table 3.

Univariate and multivariate Cox regression analyses of prognostic factors for all-cause mortality.

Variable Univariate analyses
Multivariate analyses
HR 95% CI p HR 95% CI p
SIRI (<1.28 vs. ≥1.28) 2.065 1.347–3.166 0.001 2.007 1.304–3.088 0.002
Sex (male = 1; female = 2) 0.850 0.561–1.288 0.443      
Age (years) 1.047 1.030–1.063 <0.001 1.037 1.020–1.054 <0.001
BMI (kg/m2) 1.038 0.955–1.129 0.376
Cardiovascular disease (no = 0; yes = 1) 1.644 1.094–2.471 0.017
Diabetes mellitus (no = 0; yes = 1) 2.217 1.468–3.348 <0.001
Hemoglobin (g/L) 0.996 0.986–1.007 0.498
RDW (%) 1.093 1.004–1.189 0.039
Serum creatinine (μmol/L) 0.999 0.998–1.000 0.004
Serum albumin (g/L) 0.908 0.871–0.948 <0.001 0.931 0.890–0.974 0.002
Uric acid (μmol/L) 0.999 0.997–1.001 0.494
Cholesterol (mmol/L) 1.051 0.888–1.244 0.565
Triglyceride (mmol/L) 1.079 0.925–1.259 0.334
Total Kt/V 0.748 0.501–1.117 0.156
NLR (<2.59 vs. ≥2.59) 1.546 1.028–2.325 0.037
MLR (<0.31 vs. ≥0.31) 2.314 1.484–3.068 <0.001

SIRI: systemic inflammation response index; NLR: neutrophil count/monocyte count; MLR: monocyte count/lymphocyte count; RDW: red blood cell distribution width.

In univariate Cox regression analysis, variables with p < 0.1 will be included in multivariate Cox regression.