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. 2022 Jun 28;16:909833. doi: 10.3389/fnins.2022.909833

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Copyright © 2022 Faridzadeh, Salimi, Ghasemirad, Kargar, Rashtchian, Mahmoudvand, Karimi, Zerangian, Jahani, Masoudi, Sadeghian Dastjerdi, Salavatizadeh, Sadeghsalehi and Deravi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neuroprotective effects of sage, lavender, and rosemary in Multiple sclerosis (MS) and glioblastoma. In MS, herbal medicine can inhibit Blood-Brain Barrier (BBB) permeability, T helper 17 (Th17) polarization, pro-inflammatory cytokines secretion, and axonal demyelination. In glioblastoma, herbal medicine can induce transcription of p53 and NGF, resulting in memory improvement. Sage, lavender, and rosemary can also inhibit nuclear factor κB (NF-κB), pro-inflammatory cytokines, and MDM2, which is an inhibitor of tumor suppressor p53.