TABLE 4.

Percentage of patients with DOAC concentrations outside range ^a , stratified by DOAC type and moment of measurement

DOAC type and measurement	Number of patients outside range b (%)	Outside range ≥2 times (%)
Rivaroxaban, trough levels	36/51 (71%)	18/36 (50%)
Rivaroxaban, peak levels	42/51 (82%)	14/42 (33%)
Apixaban, trough levels	28/50 (56%)	18/28 (64%)
Apixaban, peak levels	35/50 (70%)	18/35 (51%)
Dabigatran, trough levels	29/51 (57%)	16/29 (55%)
Dabigatran, peak levels	33/51 (65%)	15/33 (46%)

Abbreviation: DOAC, direct oral anticoagulant.

^a Within range is defined as a value within the 20th and 80th percentile (of full dose DOAC).

^b At least once.