Scheme 1. Reagents and conditions: a) Boc2O, THF, RT, 1 hour, 89%. b) Phthalimide, PPh3, DEAD, THF, N2, 0 °C – RT, 18 hours, 63%. c) N2H4·H2O, EtOH, 60 °C, 4 hours, 74%. d) 3-Bromobenzoyl chloride, NEt3, DCM, N2, RT, 22 hours, 77%. e) Substituted boronic acid, Pd(PPh3)4, propanol, 2 M Na2CO3 aqueous solution, N2, reflux, 20–35%. f) 4 N HCl in dioxane, RT, 65–93%.
