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. 2021 Oct 26;26(2):445–462. doi: 10.1002/ejp.1871

TABLE 2.

Potential metabolomic candidates in FM

Metabolites HMDB ID FM/control p value VIP score AUC value
Urine Hypoxanthine HMDB0000157 1.782 ± 0.241 0.0104 1.9699 0.7509
Diethylthiophosphate a HMDB0001460 0.603 ± 0.115 0.0424 1.9671 0.7540
4‐Guanidinobutanoic acid HMDB0003464 0.587 ± 0.113 0.0411 4.5964 0.7668
Serum SM(d18:1/18:0) HMDB0001348 1.294 ± 0.093 0.0122 1.9189 0.7640
Tryptophan HMDB0000929 0.862 ± 0.035 0.0433 1.5268 0.7500
Isoleucine HMDB0000172 0.804 ± 0.042 0.0088 1.0986 0.7506
PC(20:1(11Z)/18:0) HMDB0008300 0.679 ± 0.069 0.0389 1.1639 0.7593
Diethylthiophosphate a HMDB0001460 0.476 ± 0.117 0.0034 1.2454 0.8446

Data are mean ± SD unless indicated.

Abbreviations: AUC, area under the receiver‐operating characteristic curve; VIP, variable importance in projection.

a

Intersection of FM patient serum and urine.