TABLE 1.
Overview over 7T fMRI memory studies, paradigm and scanning parameters
| Authors | N | TR (ms) | TE (ms) | Voxel size (mm) | Slices | FOV (mm) | Paradigm | ROI |
|---|---|---|---|---|---|---|---|---|
| Koster et al. (2018) | 26 | 2500 | 22 | 0.8 × 0.8 × 0.8 | 28 | 205 × 205 | Inference task (memory integration) | MTL |
| Maass et al. (2015) | 22 | 2000 | 22 | 0.8 × 0.8 × 0.8 | 28 | 205 × 205 | Visual associative memory | MTL |
| Navarro Schröder et al. (2015) | 22 | 2756 | 20 | 0.9 × 0.9 × 0.92 | 96 | 210 × 210 | Spatial navigation task | MTL (EC) |
| Shah et al. (2018) | 13 | 1000 | 24 | 2 × 2 × 2 | 64 | 192 × 192 | Resting state, functional connectivity | MTL |
| Sladky et al. (2018) | 38 | 1400 | 23 | 1.5 × 1.5 × 1 | 78 | / | Emotional face viewing | Amygdala, BNST |
| Suthana, Donix, et al. (2015) | 14 | 3000 | 19 | 1 × 1 × 2 | 21 | 200 × 200 | Visual associative memory | HC |
| Theysohn et al. (2013) | 28 | 2050 | 25 | 2.5 × 2.5 × 2 | 50 | 230 × 230 | Visual associative memory | MTL |
| Barron et al. (2020) | 22 | 1512 | 20 | 1.5 × 1.5 × 1.5 | 50 | 192 × 192 | Inference task (memory integration) | MTL |
| Hodgetts et al. (2017) | 25 | 2000 | 25 | 1.2 × 1.2 × 1.2 | 30 | 192 × 192 | Perceptual oddity task, discrimination | HC and subiculum |
| Berron et al. (2017) | 20 | 2000 | 22 | 0.8 × 0.8 × 0.8 | 28 | 205 × 205 | Scene discrimination | Hippocampus |
| Finn et al. (2019) | 15 | 2500 | 27 | 0.75 × 0.75 × 0.99 | / | 130 × 130 | Working memory, delayed response task | DLPFC |
| Lawrence et al. (2018) | 21 | 3408 | 28 | 0.8 × 0.8 × 0.8 | / | 192 × 192 | Visual working memory task | V1 |
| Margalit et al. (2020) | 7 | 2200 | 22.4 | 0.8 × 0.8 × 0.8 | 84 | 160 × 129.6 | Oddball detection task, visual stimuli | VTC |
| Murphy et al. (2020) | 30 | 3000 | 28 | 0.85 × 0.85 × 1.5 | 37 | / | Emotional face matching task | Amygdala |
| Jacobs et al. (2020) | 27 | 2000 | 19 | 1.25 × 1.25 × 1.25 | 50 | / | Emotional face matching task | LC, amygdala, HC |
Note: While all studies were memory related, not all of them specifically looked for engrams.
Abbreviations: Amy: amygdala; BNST, bed nucleus of the Stria terminalis; DLPFC, dorsolateral prefrontal cortex; EC, entorhinal cortex; FOV, field of view; HC, hippocampus; LC, locus coeruleus; MTL, medial temporal lobe; N, number of participants; ROI: region of interest, that is, investigated brain area; Sub, subiculum; V1, primary visual cortex; TE, echo time; TR, repetition time.