FIGURE 1.

Illustration of the contrasting postreperfusion metabolic responses of kidney donor grafts with delayed graft function (DGF, IR injury, red curve) and grafts recovering without IR injury (no DGF) (green curve: living donor graft [intermediate ischemic period], blue curve: deceased donor graft [prolonged ischemic period]). The dashed line reflects the normal, non‐ischemic kidney. Figures adapted from Lindeman et al. ⁴ Curves represent renal vein levels of lactate (glycolysis), uracil (cellular damage), ⁵ hypoxanthine (ATP catabolism and metabolic incompetence), and isovalerylcarnitine (intermediate of branched‐chain amino acid oxidation [autophagia]). *Decrease at end of measurement window may reflect depletion of ATP pool