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Treatment sequence by drug class. (a) Tumor necrosis factor (TNF)‐α inhibitors. (b) Interleukin (IL)‐12/23 inhibitor. (c) Anti‐IL‐17 agents. (d) IL‐23p19 inhibitor. Drug classes were: TNF‐α inhibitors = etanercept, adalimumab, and infliximab; IL‐12/23 inhibitor = ustekinumab; anti‐IL‐17 agents = secukinumab, ixekizumab, and brodalumab; and IL‐23p19 inhibitor = guselkumab.
