Table 3.

Early and late WDR45-related manifestations stratified by sex.

	Male	Female
Initial symptom
Developmental delay: n	15 (71.4%)	75 (59.5%)
Seizures: n	5 (23.8%)	38 (30.2%)
Other: n	2 (9.5%)	9 (7.1%)
NA: n		9 (7.1%)
Median age at first report of developmental delay: Years	0.3 (IQR = 0.3)	1 (IQR = 1.8)
Median age at first report of seizures: Years	0.5 (IQR = 1.1)	1.3 (IQR = 1)
Median age at first report of epileptic spasms: Years	0.4 (IQR = 0.2)	0.9 (IQR = 0.9)
Median age at detection of brain iron accumulation: Years	8.2 (IQR = 18.6)	11 (IQR = 22.8)
Median age at first report of movement disorders: Years	24 (IQR = 24)	24 (IQR = 18.9)
Median age at first report of developmental regression: Years	27 (IQR = 1)	25.5 (IQR = 9.5)
Median age at first report of mental deterioration: Years	26 (IQR = 6)	26 (IQR = 8)