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. 2022 Jul 6;15:917598. doi: 10.3389/fnmol.2022.917598

FIGURE 2.

FIGURE 2

IL-17A deficiency in mice does not alter epileptogenesis. (A) Timeline showing the experimental design. (B) Representative EEG traces showing generalized seizures from IL-17A WT and IL-17A KO animals. (C) Schematic drawing of the mouse brain with locations of electrodes. Ref: reference; LPC: left parietal cortex. (D) Graphs showing the number of spontaneous recurrent seizures (SRS) per day and duration of each seizure. There was no difference in SRS frequency or duration between IL-17A WT and KO mice. n = 4 (WT) and n = 6 (KO). Detailed statistics are as follows. SRS frequency: Student’s unpaired t-test, p = 0.906, t(8) = 0.122; SRS duration: Mann–Whitney U-test, p = 0.257, U = 6,000. Data are presented as mean ± SEM. *p < 0.05, NS, not significant.