Table 5.
Univariate and multivariate analysis of clinical factors that correlate with OS of glioma patients.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | ||
| WHO grade | 634 | ||||
| G2 | 223 | Reference | |||
| G3 | 243 | 2.999 (2.007–4.480) | <0.001 | 1.723 (1.104–2.688) | 0.017 |
| G4 | 168 | 18.615 (12.460–27.812) | <0.001 | 3.880 (2.227–6.761) | <0.001 |
| IDH status | 685 | ||||
| Mut | 439 | Reference | |||
| WT | 246 | 8.551 (6.558–11.150) | <0.001 | 3.218 (2.141–4.837) | <0.001 |
| 1p/19q codeletion | 688 | ||||
| codel | 170 | Reference | |||
| non-codel | 518 | 4.428 (2.885–6.799) | <0.001 | 1.346 (0.809–2.239) | 0.252 |
| Age | 695 | ||||
| ≤60 | 552 | Reference | |||
| >60 | 143 | 4.668 (3.598–6.056) | <0.001 | 1.502 (1.103–2.046) | 0.010 |
| Gender | 695 | ||||
| Female | 297 | Reference | |||
| Male | 398 | 1.262 (0.988–1.610) | 0.062 | 1.212 (0.923–1.593) | 0.166 |
| ASF1B | 695 | ||||
| Low | 348 | Reference | |||
| High | 347 | 5.029 (3.758–6.730) | <0.001 | 1.573 (1.053–2.350) | 0.027 |
Values in bold indicate that the value is less than 0.05 and is statistically different.