Table 1.
Effects of WEPE and GA on serum biochemical values of C57BL/6 mice fed by MCD diet after 4 or 8 weeks.
| Control | MCD | MCD + GA | MCD + L-WEPE | MCD + M-WEPE | MCD + H-WEPE | Control + H-WEPE | ||
|---|---|---|---|---|---|---|---|---|
| 4 week | AST (U/L) | 92.2 ± 45.6c | 386.8 ± 127.9a | 283.2 ± 106.0b | 235.3 ± 53.8b | 292.8 ± 59.4b | 239.0 ± 49.4b | |
| ALT (U/L) | 41.3 ± 15.2c | 620.7 ± 199.8a | 454.2 ± 170.3b | 322.8 ± 90.4b | 415.7 ± 66.0b | 293.8 ± 74.1b | ||
| CHOL (mg/dL) | 91.5 ± 4.3a | 29.7 ± 5.4c | 30.0 ± 5.1c | 33.5 ± 6.8bc | 31.5 ± 2.7bc | 37.7 ± 6.5b | ||
| TG (mg/dL) | 78.7 ± 8.1a | 45.8 ± 6.1b | 47.2 ± 5.2b | 41.0 ± 8.1b | 40.8 ± 9.1b | 42.7 ± 5.0b | ||
| 8 week | AST (U/L) | 96.8 ± 28.9de | 521.7 ± 335.6a | 443.3 ± 18.9ab | 285.2 ± 73.7bc | 300.7 ± 90.2bc | 231.8 ± 87.6cd | 56.8 ± 14.8e |
| ALT (U/L) | 39.0 ± 7.8c | 760.7 ± 368.8a | 542.8 ± 121.1b | 386.2 ± 129.8b | 495.0 ± 223.6b | 347.7 ± 140.9b | 36.7 ± 8.9c | |
| CHOL (mg/dL) | 74.3 ± 12.0a | 14.3 ± 5.7bc | 12.3 ± 3.7c | 15.2 ± 5.2bc | 15.8 ± 3.4bc | 22.0 ± 4.6b | 76.5 ± 2.7a | |
| TG (mg/dL) | 57.8 ± 6.9a | 42.0 ± 5.6c | 43.0 ± 6.1c | 50.8 ± 16.9ab | 46.5 ± 8.0ab | 47.3 ± 16.0ab | 40.7 ± 6.7c |
Each value was expressed as the mean ± SD (n = 8/group).
a–e
The letters indicated statistically significant differences between the groups (p < 0.05).