| Study | Reason for exclusion |
|---|---|
| Abou‐Chebl 2015 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| ACTRN12618000509268 | Inadequate population. RCT conducted in participants with unruptured intracranial aneurysm. |
| Avitsian 2016 | Non‐randomised study design. Retrospective analysis for type of anaesthetic technique in EVT for AIS. |
| Berkhemer 2016 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Bonafe 2016 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Bracard 2016 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Campbell 2019 | A systematic review of 3 RCTs (SIESTA, ANSTROKE, and GOLIATH) that compared GA vs CSA after mechanical thrombectomy for AIS. |
| Chabanne 2020 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Crosby 2016 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Goldhoorn 2020 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Jovin 2009 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Le 2020 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Menon 2016 | Non‐randomised study design. Retrospective analysis results for RCT that compared EVT vs IV r‐tPA for AIS. |
| Moritz 2010 | Inadequate population. RCT for carotid endarterectomy. |
| NCT03737786 | Inadequate population. RCT was conducted with participants to analyse sedation collateral support in EVT for AIS. |
| NCT04517383 | Inadequate comparator. RCT that considered infarct growth after EVT for AIS in participants sedated with propofol and dexmedetomidine for 6 hours before extubation. |
| Neimark 2010 | Inadequate population. Study was conducted with participants who underwent carotid endarterectomy. |
| Nichols 2010 | Non‐randomised study design. Retrospective study comparing GA vs non‐GA for EVT in AIS. |
| Nii 2018 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Pishjoo 2019 | Non‐randomised study design. |
| Powers 2019b | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Rabinstein 2018 | Non‐randomised study design. Literature review of studies comparing GA vs non‐GA for EVT in AIS. |
| Rohde 2019 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Schönenberger 2019 | Non‐randomised study design. |
| Shan 2018 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Simonsen 2017 | Inadequate comparator. RCT analyses of population excluded for GOLIATH trial. |
| Sindelic 2004 | Inadequate population. Study conducted for carotid endarterectomy. |
| Starke 2017 | Non‐randomised trial. |
| Taqi 2019 | Non‐randomised study design. Observational case‐control study. |
| Tekle 2018 | Non‐randomised study design. Retrospective analysis results of an RCT that did not compare the type of anaesthesia. |
| Thomas 2012 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in carotid endarterectomy. |
| Wolf 2019 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Wong 2011 | Non‐randomised study design. Retrospective analysis results for type of anaesthetic in RCT that compared EVT vs IV r‐tPA for AIS. |
| Wu 2019 | Inadequate comparator. RCT compared the type of drugs (dexmedetomidine vs propofol) in MAC for EVT in AIS. |
| Yao 2009 | Inadequate population. RCT conducted with participants who used a laryngeal mask airway during anaesthesia in stent‐assisted angioplasty for extracranial and intracranial artery stenosis. |
| Zussman 2018 | Non‐randomised study design. |
AIS: acute ischaemic stroke; CSA: conscious sedation anaesthesia; EVT: endovascular treatment; GA: general anaesthesia; IV: intravenous; MAC: monitored anaesthesia care; RCT: randomised controlled trial; r‐tPA: recombinant tissue plasminogen activator.