ChiCTR2000035282.

Study name	Effects of different anesthesia on hemodynamics and prognostic in patients with stroke having endovascular treatment: a multi‐centered, prospective, randomized controlled study
Methods	Setting: multicentre, China Design: RCT, 2 arms, parallel assignment, open‐label Start date: 26 June 2020
Participants	240 men and women aged 18–85 years Inclusion criteria > 24 hours after the onset of stroke Independent function before stroke; Rankin Scale score ≤ 2 points  Above primary school level  Able to communicate and sign informed consent.  Exclusion criteria Hypersensitivity to anaesthetics or analgesics  People who require endotracheal intubation to maintain breathing or have undergone endotracheal intubation GCS ≤ 8 NIHSS scores > 30 or < 8  Severe agitation or seizure Loss of airway protective reflexes or vomiting, or both
Interventions	Experimental: GA Comparator: LA
Outcomes	Primary outcome Neurological outcome mRS after 3 months Secondary outcomes Periprocedural mortality Mean arterial pressure
Starting date	26 June 2020
Contact information	Chen Jing  Department of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, China +86 13607815280/352880721@qq.com
Notes	ChiCTR2000035282