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. 2022 Jul 20;2022(7):CD013690. doi: 10.1002/14651858.CD013690.pub2

DRKS00006801.

Study name Impact of anesthesia during endovascular treatment of acute ischemic stroke
Methods Setting: single‐centre, Germany
Design: RCT, 2 arms, parallel assignment, open‐label
Start date: 13 October 2014
Participants 130 men and women aged 18–85 years
Inclusion criteria
  • AIS with the indication for endovascular clot retrieval

  • Anterior circulation stroke

  • Acute focal neurological deficit

  • Spontaneous breathing


Exclusion criteria
  • Intracerebral tumour

  • Intracerebral haemorrhage

  • Severe stroke (NIHSS > 25)

  • Seizure at beginning of treatment

  • Significant trauma within the last 3 months

  • Intracranial surgery in medical history

  • Blood glucose < 50 mg/dL or > 400 mg/dL

  • Alcohol abuse

  • Chronic pain

  • Severe systemic infections

  • Dementia (mRS ≥ 3)

Interventions Experimental: CSA
Comparator: GA
Outcomes Primary outcome
  • Neurological outcome mRS after 3 months


Secondary outcomes
  • Neurological outcome on discharge from hospital mortality rate (in hospital, after 3 months)

  • Duration of intensive treatment

  • Time to start the definitive neuroradiological intervention

  • Rate of recanalisation

Starting date 13 October 2014
Contact information Dr Kathrin Waurick
Universitätsklinikum Münster Klinik für Anästhesiologie, Germany
+49‐251‐83‐47255; k.broeking at gmx.com
Notes DRKS00006801