Table 2.

Regions across the 20 fiber tracts where white matter measures differ significantly between PTSD patients and TENP controls

Diffusion measures/fiber tracts	TENP	PTSD
Left uncinate fasciculus (Nodes 27–44)
Fractional anisotropy	0.424 ± 0.064	0.394 ± 0.051
Radial diffusivity	0.525 ± 0.082	0.560 ± 0.062
Mean diffusivity	0.696 ± 0.079	0.723 ± 0.064
Right anterior thalamic radiation (Nodes 84–90)
Fractional anisotropy	0.454 ± 0.058	0.424 ± 0.048
Radial diffusivity	0.540 ± 0.056	0.567 ± 0.055

Note: Measurements presented as mean ± SD. Regions were considered abnormal if they exhibited significant between‐group differences (p < .05) using permutation‐based analysis (10,000 permutations) in FSL Randomize. Nodes are defined by dividing each tract into 100 equal segments between the beginning and termination waypoint regions of interest along the given tract.

Abbreviations: PTSD, posttraumatic stress disorder; TENP, trauma‐exposed non‐PTSD controls.