Figure 1.

Heatmap indicating keratinocytes as a possible disease driver of HS. The heatmap was generated from the normalized gene expression levels of significantly differentially expressed target molecules derived from our RNASeq data set of healthy and non‐lesional and lesional HS samples. The highly increased expression levels in lesional HS were obvious while non‐lesional HS and healthy AGR skin seemed to be similar. KC‐related AMPs were highly upregulated even in non‐lesional HS skin, indicating keratinocytes as a possible disease driver cell. Abbreviations: KC, keratinocyte; Th, T helper.