TABLE 1.
Patient characteristics of adults with and without HA, and adults with and without HA with objective symptoms
| Characteristics | Total | HA | No HA | P‐value† | Objective HA | Subjective/ No HA | P‐value† |
|---|---|---|---|---|---|---|---|
| N=89 | N=46 | N=43 | N=17 | N=72 | |||
| Age (years), mean (±SD) | 33 (±13) | 32 (±11) | 35 (±15) | 0.282 | 32 (±11) | 33 (±14) | 0.789 |
| Male sex | 26 (29) | 10 (22) | 16 (37) | 0.109 | 2 (12) | 24 (33) | 0.079 |
| Asthma | 47 (53) | 25 (54) | 22 (51) | 0.764 | 12 (71) | 35 (49) | 0.103 |
| Atopic dermatitis | 52 (58) | 31 (67) | 21 (49) | 0.076 | 11 (65) | 41 (57) | 0.559 |
| Allergic rhinitis | 79 (89) | 46 (100) | 33 (77) | 0.001 | 17 (100) | 62 (86) | 0.103 |
| Birch pollen sensitization* | 77 (90) | 41 (91) | 36 (88) | 0.617 | 14 (82) | 63 (91) | 0.280 |
|
sIgE level in KUA/L, median (IQR) | |||||||
| Hazelnut extract | 4.60 (1.32–14.05) | 5.00 (1.33–15.20) | 4.30 (1.22–12.90) | 0.543 | 3.46 (0.34–8.85) | 5.15 (1.46–15.45) | 0.226 |
| Cor a 1 | 4.70 (0.74–17.70) | 4.60 (0.69–18.00) | 4.70 (0.76–18.80) | 0.974 | 2.93 (0.22–7.85) | 7.30 (1.35–21.78) | 0.098 |
| Cor a 8 | 0.00 (0.00–0.05) | 0.00 (0.00–0.02) | 0.00 (0.00–0.09) | 0.657 | 0.00 (0.00–0.02) | 0.00 (0.00–0.08) | 0.313 |
| Cor a 9 | 0.00 (0.00–0.14) | 0.01 (0.00–0.34) | 0.00 (0.00–0.08) | 0.306 | 0.14 (0.00–1.59) | 0.00 (0.00–0.08) | 0.012 |
| Cor a 14 | 0.00 (0.00–0.09) | 0.00 (0.00–0.53) | 0.00 (0.00–0.05) | 0.472 | 0.05 (0.00–0.87) | 0.00 (0.00–0.06) | 0.067 |
Values are expressed as n (%) unless otherwise specified. *Sensitization to birch pollen as determined by skin prick testing, ImmunoCAP (IgE to birch extract ≥0.35 KU/L) or ISAC (IgE to Bet v 1 ≥0.3 IU/L). Data were available for 86/89 subjects. †Explorative analyses, no correction for multiple testing. HA, hazelnut allergy; SD, standard deviation; IQR, interquartile range.