Figure 3.

Effects of Kir channel blockers on AVP-elicited inward currents recorded from DG GCs. A, Current trace recorded from a DG GC in response to bath application of Ba²⁺ (500 μm) alone and concomitant application of AVP. B, Current trace recorded from a DG GC in response to bath application of ML 133 (30 μm) alone and coapplication of AVP. C, Current trace recorded from a DG GC in response to bath application of SCH23390 (40 μm) alone and coapplication of AVP. D, Current trace recorded from a DG GC in response to bath application of glibenclamide (100 μm) alone and coapplication of AVP. E, Summary graph showing the effects of Kir channel blockers on AVP-induced inward currents. The shaded bar was the averaged inward currents evoked by AVP in control condition pooled from the control experiment conducted for each individual pharmacological experiment. *p = 0.018, ****p < 0.0001 versus AVP alone, one-way ANOVA followed by Dunnett’s test.