Table 3.
The number of IgG4‐positive cells and IgG4/IgG ratio in PC‐iMCD
| Lymph node (n = 39) | Lung (n = 19) | |
|---|---|---|
| The number of IgG4‐positive cell/HPF (mean ± SD) | 124 ± 87 | 103 ± 64 |
| >10/HPF, n (%) | 39 (100) | 18 (94.7) |
| >50/HPF, n (%) | 35 (89.7) | 15 (78.9) |
| >100/HPF, n (%) | 21 (53.8) | 9 (47.4) |
| IgG4/IgG ratio (mean ± SD) | 31.6 ± 20.8 | 43.0 ± 25.8 |
| IgG4/IgG ratio >40%, n (%) | 8 (20.5) | 8 (42.1) |
| >50/HPF and IgG4/IgG ratio >40%, n (%) | 8 (20.5) | 8 (42.1) |
| >100/HPF and IgG4/IgG ratio >40%, n (%) | 8 (20.5) | 7 (36.8) |
Note: The number of IgG4‐positive cells (/HPF) is the average of three different HPFs with the highest density.
Abbreviations: HPF, high‐power field; Ig, immunoglobulin; PC‐iMCD, plasma cell type idiopathic multicentric Castleman disease.