FIGURE 5.

(A) Effects of vehicle and milvexian on carotid blood flow (expressed as % of control carotid blood flow). In the treatment protocol, vehicle or milvexian was given IV (bolus + infusion) at 15 min after the initiation of arterial thrombosis. Means ± SEM and n = 6 per group. (B) Effects of ASA, milvexian, and combination of ASA and milvexian on CBT model in rabbits. ASA (4 mg/kg/h IV), milvexian (1 mg/kg + 0.67 mg/kg/h IV). Means ± SEM and n = 6 per group. ASA, aspirin; CBT, cuticle bleeding time; SEM, standard error of the mean