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. 2021 Nov 24;89(12):1711–1721. doi: 10.1002/prot.26257

FIGURE 3.

FIGURE 3

T1044: Comparison of the number of effective alignments (Neff) per residue for each MSA, derived both from domain sequences and from cropping the full sequence MSA. Four domains (T1033, T1039, T1040, and T1043) substantially benefit from using the full sequence MSA. The dashed green line shows the approximate 30 alignment threshold considered sufficient for a good prediction with AlphaFold