TABLE 3.

Molecular functions, biological processes, and related pathways of the 10 differentially expressed proteins (DEPs) among the three groups of Sham, I/R, and HS + I/R.

DEPs	Molecular functions	Biological process and related pathways
Adgb	Oxygen carrier and binding	NO metabolism, peroxidase activity
Cbr1	Oxidoreductase activity	Tetrahydrobiopterin biosynthetic process, ROS biosynthetic process, NO metabolism
Decr1	Dodecenoyl-CoA delta-isomerase activity, acyl-CoA dehydrogenase activity, oxidoreductase activity	Fatty acid beta-oxidation, carnitine metabolic process, oxidative stress and lipid peroxidation
Eif5	Translation initiation factor binding/activity	Eukaryotic translation initiation, GTP hydrolysis, response to stress
Uchl5	Ubiquitin carboxyl-terminal hydrolase activity	Oxygen-dependent proline hydroxylation of HIF-α, IL-1 signaling, neutrophil degranulation
Lmo7	Muscle alpha-actinin binding, actin binding, metal ion binding	Adherens junction, regulation of actin cytoskeleton
Bdh1	Hydroxymethylglutaryl-CoA lyase activity, 3-hydroxybutyrate dehydrogenase activity	Ketone body metabolism, fatty-acid beta-oxidation, acyl-CoA metabolic process, response to stress
Ckmt2	Porin activity, creatine kinase activity	Couples ATP production to phosphocreatine, calcium signaling, NOD-like receptor signaling pathway
COX7A	Cytochrome-c oxidase activity	Mitochondrial electron transport, cytochrome c to oxygen, ubiquinol to cytochrome c, oxidative phosphorylation
RT1-CE1	MHC class I protein complex binding	Antigen processing and presentation, T cell receptor signaling pathway, cell adhesion molecules, adaptive immune system

NO, nitric oxide; HIF-α, hypoxia-inducible factor-α