Table 4.
Patients’ demographics and characteristics by CD4/CD8 ratio stratification at diagnosis of AIDS-related lymphoma (n = 138).
| Variables | CD4/CD8 ratio | ||
|---|---|---|---|
| ≥0.41(n = 46, %) | <0.41(n = 92, %) | P | |
| Age > 60 | 13 (28.26) | 24 (26.87) | 0.006 |
| Male | 31 (67.39) | 81 (88.04) | 0.005 |
| Prior history of HIV | 22 (47.83) | 11 (11.96) | 0.022 |
| CD4 T cells < 300 | 19 (41.30) | 83 (90.22) | 0.368 |
| LDH > 250 | 34 (73.91) | 72 (78.26) | 0.003 |
| ECOG PS > 1 | 16 (34.78) | 38 (41.30) | 0.011 |
| Ann Arbor stage III/IV | 15 (32.61) | 45 (48.91) | 0.408 |
| Extranodal sites > 1 | 11 (23.91) | 24 (26.09) | 0.413 |
| Bulky mass (present) | 18 (39.13) | 43 (46.74) | 0.013 |
| B symptoms (present) | 6 (13.04) | 16 (17.39) | 0.046 |
| LMR < 2.33 | 20 (43.48) | 47 (51.09) | 0.029 |
| PLR ≥ 250 | 14 (30.43) | 32 (34.78) | 0.026 |
| RDW ratio ≥ 1.03 | 14 (30.43) | 31 (33.70) | 0.577 |
| Hb/RDW < 8.5 | 25 (54.35) | 49 (53.26) | 0.004 |
| ESR ≥ 80 | 7 (15.22) | 22 (23.91) | 0.018 |
| ALB < 32 | 11 (23.91) | 36 (39.13) | 0.036 |
| BMI < 18.5 | 11 (23.91) | 18 (19.57) | 0.450 |
| IPI > 2 | 14 (30.43) | 37 (40.22) | 0.103 |
| aaIPI > 1 | 20 (43.48) | 51 (55.43) | 0.017 |
| NCCN-IPI > 3 | 17 (36.96) | 39 (42.39) | 0.043 |
LDH, lactate dehydrogenase; ECOG PS, Eastern Cooperative Oncology Group performance status; LMR, lymphocyte to monocyte ratio; PLR, platelet to lymphocyte ratio; RDW ratio, red cell distribution width ratio; Hb/RDW, hemoglobin to red cell distribution width ratio; ESR, erythrocyte sedimentation rate; ALB, albumin; BMI, body max index; IPI, International Prognostic Index; aaIPI, age-adjusted IPI; NCCN-IPI, National Comprehensive Cancer Network IPI. P-value < 0.05.