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. 2022 Jul 20;12(7):e989. doi: 10.1002/ctm2.989

FIGURE 12.

FIGURE 12

The schematic overview illustrates the mechanistic basis for the observational study results. Cancer‐associated fibroblast (CAF)‐derived miR‐20a is transmitted into non‐small‐cell lung cancer (NSCLC) cells through exosomes and can therein modulate the PTEN/PI3K‐AKT signalling axis to influence tumour growth and chemoresistance