TABLE 1.
Patient Characteristics
| Patient characteristics |
PASC a n = 13 |
PAAC b n = 13 |
Healthy controls n = 20 |
P‐value c |
|---|---|---|---|---|
| Age, median (range) | 49 (24–73) | 48 (22–59) | 36 (18–51) | 0.5670 |
| Female sex, n (%) | 12 (92%) | 11 (85%) | 6 (30%) | 1.0000 |
| Race | ||||
| Black, n (%) | 1 (8%) | 0 (0%) | 0 (0%) | 1.0000 |
| Caucasian/non‐Hispanic, n (%) | 12 (92%) | 11 (85%) | 20 (100%) | 1.0000 |
| Hispanic, n (%) | 0 (0%) | 2 (15%) | 0 (0%) | 1.0000 |
| SARS‐CoV‐2 ELISA IgG, median (range) | 4.3 (0.3–11.7) | 3.8 (1.2–6.7) | N/A d | 0.2434 |
| Days between positive PCR test and serum sample collection, median (range) | 62 (39–305) | 34 (22–322) | N/A d | 0.1851 |
| Self‐reported long‐term symptom, n (%) | 13 (100%) | 0 (0%) | N/A d | N/A |
| Fatigue | 11 (85%) | 0 (0%) | ||
| Body aches | 6 (46%) | 0 (0%) | ||
| Change or loss in taste/smell | 6 (46%) | 0 (0%) | ||
| Anxiety | 4 (31%) | 0 (0%) | ||
| Shortness of breath | 4 (31%) | 0 (0%) | ||
| Brain fog | 3 (23%) | 0 (0%) | ||
| Headaches | 3 (23%) | 0 (0%) | ||
| Sore throat | 2 (15%) | 0 (0%) | ||
| Tachycardia | 2 (15%) | 0 (0%) | ||
| Anemic | 1 (8%) | 0 (0%) | ||
| Dyspnea | 1 (8%) | 0 (0%) | ||
| Joint pain | 1 (8%) | 0 (0%) | ||
| Insomnia | 1 (8%) | 0 (0%) | ||
Abbreviations: PAAC, post‐acute asymptomatic of COVID‐19; PASC, post‐acute sequelae of COVID‐19.
a
PASC patients were defined as SARS‐CoV‐2 negative with persistent symptoms for at least ~1 month after confirmed positive infection.
b
PAAC patients were defined as SARS‐CoV‐2 negative with no symptoms after confirmed positive infection.
c
Unpaired two‐tailed t test between PASC vs PAAC performed on numerical values; Fisher's exact test performed on proportions.
d
Data are not collected as part of study.