FIGURE 1.
Change in HbA1c level from baseline by A, adherence to and B, persistence with antidiabetic medication in studies reporting this outcome. Bars with an asterisk indicate statistically significant results for adherent/persistent versus nonadherent/nonpersistent patients (P < 0.05). Min et al 78 and Reynolds et al 94 did not report P values for adherent versus nonadherent patients. Eliasson et al 112 and Melzer‐Cohen et al 75 did not report P values for persistent versus nonpersistent patients. For adherence, studies were included if they reported change in HbA1c (follow‐up times varied, as indicated for each study); for persistence, studies were included if they reported change in HbA1c over 6, 12 or 24 months. aData shown are means, except for Min et al 78 which are median. HbA1c, glycated haemoglobin