Table 3. Single-molecule fluorescence resonance energy transfer (smFRET) state occupancy data and statistics.
Table 3—source data 1. Source data for Table 3.
elife-78982-table3-data1.xlsx (11.6KB, xlsx)
| Modulator | Glut (μM) | State (#) | Mean occupancy | SEM |
|---|---|---|---|---|
| None | 0 | 1 | 0.36067 | 0.048 |
| None | 0 | 2 | 0.56526 | 0.02692 |
| None | 0 | 3 | 0.06615 | 0.02385 |
| None | 0 | 4 | 0.00792 | 0.00792 |
| None | 15 | 1 | 0.01932 | 0.01049 |
| None | 15 | 2 | 0.27699 | 0.06688 |
| None | 15 | 3 | 0.29899 | 0.01579 |
| None | 15 | 4 | 0.4047 | 0.09147 |
| None | 1000 | 1 | 0.00642 | 0.00292 |
| None | 1000 | 2 | 0.07841 | 0.01209 |
| None | 1000 | 3 | 0.31131 | 0.02404 |
| None | 1000 | 4 | 0.60386 | 0.01743 |
| 10 μM BINA | 0 | 1 | 0.30527 | 0.02468 |
| 10 μM BINA | 0 | 2 | 0.51994 | 0.04492 |
| 10 μM BINA | 0 | 3 | 0.14826 | 0.04699 |
| 10 μM BINA | 0 | 4 | 0.02653 | 0.01748 |
| 10 μM BINA | 15 | 1 | 0.01424 | 0.00761 |
| 10 μM BINA | 15 | 2 | 0.11217 | 0.01526 |
| 10 μM BINA | 15 | 3 | 0.3367 | 0.07918 |
| 10 μM BINA | 15 | 4 | 0.53688 | 0.07621 |
| 10 μM BINA | 1000 | 1 | 0.00296 | 0.00154 |
| 10 μM BINA | 1000 | 2 | 0.03751 | 0.00782 |
| 10 μM BINA | 1000 | 3 | 0.21791 | 0.01663 |
| 10 μM BINA | 1000 | 4 | 0.74162 | 0.01093 |
| 5 μM MNI-137 | 0 | 1 | 0.74861 | 0.02014 |
| 5 μM MNI-137 | 0 | 2 | 0.22198 | 0.01316 |
| 5 μM MNI-137 | 0 | 3 | 0.02038 | 0.01004 |
| 5 μM MNI-137 | 0 | 4 | 0.00903 | 0.00541 |
| 5 μM MNI-137 | 15 | 1 | 0.10387 | 0.02484 |
| 5 μM MNI-137 | 15 | 2 | 0.74937 | 0.01688 |
| 5 μM MNI-137 | 15 | 3 | 0.12724 | 0.01026 |
| 5 μM MNI-137 | 15 | 4 | 0.01952 | 0.00254 |
| 5 μM MNI-137 | 1000 | 1 | 0.00207 | 0.000954 |
| 5 μM MNI-137 | 1000 | 2 | 0.5597 | 0.02561 |
| 5 μM MNI-137 | 1000 | 3 | 0.33098 | 0.03204 |
| 5 μM MNI-137 | 1000 | 4 | 0.10725 | 0.00734 |