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. 2021 Dec 1;49(1):568–578. doi: 10.1002/mp.15348

TABLE 1.

Values of SF 2 (Surviving Fraction at 2 Gy), MID, SER, and DEF 40% (dose enhancement factor at 40% surviving fraction) for MDA‐MB‐231 cells treated at two concentrations of 15 nm Aurovist™ AuNPs and three qualities of X‐rays

X‐ray beam quality 15 nm AuNP concentration SF 2 MID SER DEF 40%
100 kV 0 μg/mL 0.36 ± 0.03 1.26 1.00
100 μg/mL (4.87 nM) 0.30 ± 0.03 1.16 1.10 1.17 ± 0.08
200 μg/mL (9.74 nM) 0.28 ± 0.01 1.05 1.20 1.34 ± 0.02
190 kV 0 μg/mL 0.30 ± 0.02 1.26 1.00
100 μg/mL (4.87 nM) 0.23 ± 0.01 1.16 1.08 1.15 ± 0.06
200 μg/mL (9.74 nM) 0.18 ± 0.01 1.05 1.20 1.33 ± 0.06
6 MV 0 μg/mL 0.36 ± 0.04 1.10 1.00
200 μg/mL (9.74 nM) 0.32 ± 0.03 1.06 1.04 1.14 ± 0.06