TABLE 1.
Clinical and surgical characteristics of donors and recipients
| Variable | Control (n = 11) | NAS (n = 18) | HAT (n = 13) | p Values |
|---|---|---|---|---|
| Donor characteristics | ||||
| Age (years) | 50 (45‐53) | 45 (39‐56) | 53 (49‐59) | 0.69 |
| Sex | ||||
| Male | 2 (20%) | 10 (56%) | 5 (42%) | 0.2 |
| Female | 8 (80%) | 8 (44%) | 7 (58%) | |
| GGT (U/L) | 14 (9‐31) | 20 (17‐59) | 27 (14‐83) | 0.25 |
| Type of donor | ||||
| DCD | 0 | 7 (39%) | 1 (8%) | 0.03 c |
| DBD | 9 (82%) | 11 (61%) | 11 (85%) | |
| Cold ischemia time (hour:minute) | 10:02 (7:39‐13:52) | 8:34 (7:21‐10:37) | 8:19 (7:06‐10:06) | 0.22 |
| Warm ischemia time (hour:minute) | 0:54 (0:46‐0:57) | 0:51 (0:39‐1:02) | 0:47 (0:35‐0:55) | 0.31 |
| Recipient characteristics | ||||
| Age (years) a | 41 (22‐50) | 47 (35‐56) | 52 (40‐56) | 0.13 |
| Sex | ||||
| Male | 5 (45%) | 7 (39%) | 5 (38%) | 0.93 |
| Female | 6 (55%) | 11 (61%) | 8 (62%) | |
| MELD score | 20 (15‐23) | 22 (15‐25) | 19 (12‐23) | 0.29 |
| Days between first and second transplant | 1,512 (854‐3,040) | 386 (143‐2,293) | 7 (5‐31) | 0.01 d |
| Bile duct anastomosis at first OLT | ||||
| Duct to duct | 11 (100%) | 16 (89%) | 9 (70%) | 0.22 |
| Hepaticojejunostomy | 0 | 2 (11%) | 3 (23%) | |
| Surgical technique | ||||
| Classical | 4 (36%) | 3 (17%) | 1 (8%) | 0.35 |
| Piggyback | 6 (55%) | 15 (83%) | 12 (92%) | |
| Laboratory serum values b | ||||
| AST (U/L) | 55 (30‐148) | 105 (70‐157) | 366 (90‐2,036) | 0.07 |
| ALT (U/L) | 54 (19‐100) | 69 (54‐117) | 614 (88‐2,262) | 0.00 d , e |
| GGT (U/L) | 91 (58‐431) | 344 (202‐734) | 92 (52‐380) | 0.3 |
| ALP (U/L) | 133 (78‐265) | 484 (205‐756) | 143 (111‐244) | 0.24 |
| Bilirubin (µmol/L) | 53 (15‐607) | 169 (55‐274) | 49 (20‐111) | 0.37 |
| Albumin (g/L) | 34 (29‐35) | 34 (29‐38) | 18 (12‐25) | 0.00 d , e |
Data are expressed as median and interquartile range; p values <0.05 are in bold. In some groups, numbers do not add up because of missing data.
a
At time of first transplant.
b
Before retransplantation.
c
Post hoc test showed a p < 0.05 between control and NAS groups.
d
Post hoc test showed a p < 0.05 between control and HAT groups.
e
Post hoc test showed a p < 0.05 between NAS and HAT groups.
Abbreviations: MELD, Model for End‐Stage Liver Disease; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transferase.