TABLE 1.
Baseline Demographic Comparisons between SFN Main and Validation Cohorts
| Characteristic | Main Cohort | Validation Cohort | p |
|---|---|---|---|
| Mean (± SD) or n (% of total) | |||
| Total | 58 | 33 | |
| Gender | |||
| M | 31 (53.4%) | 7 (21.2%) | 0.016 a |
| F | 27 (46.6%) | 26 (78.8%) | |
| Age, yr | 50.0 (±13.6) | 46.3 (±12.5) | 0.209 |
| Symptom description and signs | |||
| Positive | 30 (51.7%) | 25 (75.8%) | 0.051 |
| Negative | 13 (22.4%) | 2 (6.1%) | |
| Both positive and negative | 15 (25.9%) | 6 (18.2%) | |
| Topography based on symptoms | |||
| Length dependent | 26 (44.8%) | 21 (85.0%) | 0.116 |
| Non–length dependent | 30 (51.7%) | 12 (15.0%) | |
| Not available | 2 (3.45%) | 0 (0%) | |
| Autonomic symptoms b | |||
| No | 14 (24.1%) | 16 (48.5%) | 0.103 |
| Yes | 32 (55.2%) | 17 (51.5%) | |
| Not available | 12 (20.7%) | ||
| SFN diagnostic category | |||
| Possible | 6 (10.3%) | 1 (3.0%) | 0.065 |
| Probable | 9 (15.5%) | 2 (3.0%) | |
| Definite | 43 (74%) | 31 (93.9%) | |
| Etiology | |||
| Idiopathic | 34 (58.6%) | 18 (54.5%) | 0.826 |
| Secondary causes | 24 (41.4%) | 15 (45.5%) | |
a
Statistically significant.
b
Presence or absence of chronic diarrhea, constipation, urinary hesitancy or incontinence in the absence of other urological disorders, hyper‐/hypohidrosis, dry eyes/mouth/skin, chronic postural intolerance or orthostatic blood pressure drop, and chronic palpitations in the absence of cardiological disease.
F= female; M= male; SD= standard deviation; SFN= small fiber neuropathy.