Extended Table 3. Substrate specificity of differentially expressed histone methylating genes.

List of differentially expressed (p<0.2) genes between soft and stiff PDMS, as determined by RNAseq, with the GO term association histone methylation (GO:0016571). Shown are substrate specificities for mono (1), di (2), tri (3) or any methylation of the respective target histone residue as obtained from either UniProt or AmiGO database. H3K9 residues were amongst the most prevalent substrates.

Gene	Ensembl ID	Substrate specificity	Source	FC	p-value
Ehmt1	ENSMUSG00000036893	H3K9me1/2	UniProt	0.847	0.0185
Paxbp1	ENSMUSG00000022974	H3K4me2/3	UniProt	0.751	0.0666
Pwp1	ENSMUSG00000001785	H3K20me3	AmiGO	0.860	0.0797
Setdb1	ENSMUSG00000015697	H3K9me3	UniProt	0.823	0.0830
Rtf1	ENSMUSG00000027304	H3K4me3	UniProt	1.127	0.1119
Setd1a	ENSMUSG00000042308	H3K4me	UniProt	0.670	0.1190
Setd1b	ENSMUSG00000038384	H3K4me	UniProt	0.193	0.1573
Eed	ENSMUSG00000030619	H3K9me, H3K27me	UniProt	0.719	0.1687
Arid4b	ENSMUSG00000039219	H3K9me3, H3K20me3	AmiGO	1.158	0.1881