Extended Table 6.
Characteristics and physiological parameters of human patients.
No heart failure | Nonischemic cardiomyopathy | ||||||
---|---|---|---|---|---|---|---|
ID # | 1549 | 1545 | 1739 | 1720 | 1792 | 1737 | p-value |
AGE | 49 | 44 | 52 | 44 | 66 | 69 | 0.285 |
Weight (kg) | 104 | 89 | 90 | 110 | 65 | 120 | 0.839 |
Height (cm) | 180.3 | 182.9 | 175 | 185 | 168 | 183 | 0.909 |
BMI | 31.0 | 26.6 | 29.4 | 32.1 | 23.0 | 35.8 | 0.824 |
Physiology | |||||||
Left Ventricle Mass (g) | 213 | 246 | 213 | 280 | 290 | 383 | 0.092 |
Heart Weight (g) | 383 | 326 | 352 | 500 | 465 | 609 | 0.045 |
LV/Ht (%) | 55.6 | 75.5 | 60.5 | 56.0 | 62.4 | 62.9 | 0.193 |
LV ejection fraction (%) | 55 | 55 | 65 | 13 | 17.5 | 25 | 0.001 |
Creatinine (mg/dL) | 2.1 | 1.1 | 0.72 | 1.17 | 1.42 | 1.31 | 0.989 |
Enrichment | |||||||
DAPI | 1.80 | 2.28 | 2.33 | 1.10 | 1.54 | 1.20 | 0.018 |
H3K27me3 | 3.30 | 1.45 | 3.58 | 0.82 | 1.89 | 1.29 | 0.151 |
H3K9me3 | 2.18 | 1.92 | 2.70 | 0.77 | 0.99 | 1.08 | 0.018 |