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. 2022 Jul 13;2022:6813017. doi: 10.1155/2022/6813017

Figure 1.

Figure 1

(a) With the increase of 6-OHDA concentration, the survival rate of SH-SY5Y cells decreased gradually. And the survival rate of SH-SY5Y cells was 50% of the control group when the 6-OHDA concentration was 75 μmol/L. ###P < 0.001, ##P < 0.01 vs. control. (b) Different concentrations of semaglutide and liraglutide had no significant effect on the survival rate of SH-SY5Y cells compared with the control group. (c) Semaglutide and liraglutide reverse cytotoxicity in 6-OHDA-treated SH-SY5Y cells, whereas semaglutide is more effective. Cells were treated with 6-OHDA (75 μM) for 24 (h). ###P < 0.001 vs. control. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 vs. 6-OHDA treatment. &P < 0.05 compared with the 6-OHDA + liraglutide group. An MTT assay was employed to measure cell viability. Data was expressed as mean ± standard deviation.