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. 2022 Jul 13;2022:6813017. doi: 10.1155/2022/6813017

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Copyright © 2022 Dong-xing Liu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Changes in the ΔΨm levels in SH-SY5Y cells. (a) Detection of the percentage of green fluorescence of JC-1 by flow cytometry. Green fluorescence indicates a low mitochondrial membrane potential (ΔΨm). (b) The green fluorescence of JC-1 was upregulated in the 6-OHDA group (^###P < 0.001 vs. the control group). Semaglutide and liraglutide normalized the green fluorescence of JC-1 (^∗∗∗P < 0.001 vs. 6-OHDA group) and semaglutide was significantly more effective (^&P < 0.05 vs. 6-OHDA + liraglutide group). All data were expressed as mean ± standard deviation (n = 4).