Table 3.
Treatment of in vitro drug release data with different kinetic equations.
Batches | Mathematical model (r2) | |||||
---|---|---|---|---|---|---|
Zero order | First order | Hixson-Crowell | Higuchi plot | Korsmeyer-Peppas | Release exponents | |
DF1 | 0.985 ± 0.048 | 0.928 ± 0.087 | 0.987 ± 0.089 | 0.952 ± 0.043 | 0.895 ± 0.043 | 1.201 ± 0.192 |
DF2 | 0.994 ± 0.056 | 0.931 ± 0.087 | 0.991 ± 0.051 | 0.951 ± 0.047 | 0.861 ± 0.033 | 1.567 ± 0.091 |
DF3 | 0.992 ± 0.091 | 0.903 ± 0.076 | 0.972 ± 0.043 | 0.973 ± 0.068 | 0.842 ± 0.081 | 1.786 ± 0.213 |
DF4 | 0.992 ± 0.055 | 0.913 ± 0.076 | 0.982 ± 0.054 | 0.973 ± 0.032 | 0.881 ± 0.018 | 1.887 ± 0.134 |
DF5 | 0.990 ± 0.061 | 0.913 ± 0.064 | 0.992 ± 0.067 | 0.960 ± 0.078 | 0.907 ± 0.043 | 1.524 ± 0.157 |
DF6 | 0.996 ± 0.075 | 0.876 ± 0.092 | 0.973 ± 0.067 | 0.983 ± 0.078 | 0.916 ± 0.032 | 1.096 ± 0.155 |