Table 1. Baseline characteristics.
| Variable | LD-SCCE, number (%), n = 29 | ED-SCCE, number (%), n = 27 |
|---|---|---|
| Patient characteristics | ||
| 1. Age (in years) Median Interquartile range (IQR) |
58 50.5–66.5 |
57 51–64 |
| 2. Sex Male Female |
18 (62.1%) 11 (37.9%) |
15 (55.6%) 12 (44.4%) |
| 3. Comorbidity Yes No |
14 (48.3%) 15 (51.7%) |
10 (37.1%) 17 (62.9%) |
| 4. ECOG PS 0–1 ≥2 |
28 (96.5%) 1 (3.5%) |
21 (77.8%) 6 (22.2%) |
| 5. Addictiona Tobacco chewer Smoker Alcohol None |
14 (48.3%) 11 (37.9%) 2 (6.9%) 4 (13.8%) |
11 (40.7%) 12 (44.4%) 5 (18.5%) 4 (14.8%) |
| Tumour characteristics | ||
| 6. Location Cervical + upper Middle Lower + GEJ |
4 (13.8%) 18 (62.1%) 7 (24.1%) |
3 (11.1%) 13 (48.1%) 11 (40.7%) |
| 7. Histology Pure small cell carcinoma Mixed histology |
26 (89.7%) 3 (10.3%) |
25 (92.6%) 2 (7.4%) |
| 9. Median length in cm | 6.2 | 7.4 |
| 10. Skip lesion Yes No |
1 (3.4%) 28 (96.6%) |
2 (7.4%) 25 (92.6%) |
| 11. Regional lymph node involvement Yes No |
26 (89.7%) 3 (10.3%) |
26 (96.3%) 1 (3.7%) |
| 12. Metastatic sites Liver Non-regional lymph node Lungs Bone Bone marrow Brain |
NA NA NA NA NA NA |
17 (62.9%) 13 (48.1%) 7 (25.9%) 6 (22.2%) 5 (18.5%) 1 (3.7%) |
| 13.Number of metastatic sites 1 2 ≥3 |
NA NA NA |
13 (48.1%) 7 (25.9%) 7 (25.9%) |
|
Laboratory parameters
Median (IQR) Median (IQR) | ||
| 14. Haemoglobin in gm/dl | 12.3 (11.3–14.3) | 12.6 (11.6–14.1) |
| 15. Albumin in gm/dl | 4.1 (3.8–4.3) | 3.9 (3.6–4.2) |
| 16. Serum alkaline phosphatasein U/L | 98 (81–113) | 112 (87–148.5) |
| 17. LDH in U/L | 170 (152–196.5) | 328 (203–689) |
Abbreviations: LD-SCCE: Limited-stage disease small cell carcinoma of the oesophagus; ED-SCCE: Extensive-stage disease small cell carcinoma of the oesophagus; ECOG PS: Eastern Cooperative Oncology Group performance status; GEJ: Gastroesophageal junction; NA: Not applicable; LDH: Lactate dehydrogenase
a
Sum is more than the total number of patients as few patients had a history of more than one type of substance abuse