Table 2.

Parameter estimates for thrombospondin-1 in the final PD model

Parameters	Units	Estimate	95% CI	Shrinkage (%)
Population parameters
EC50	ng/mL	284	122–724	–
EBASE	ng/mL/106 platelets	43.8	39.7–48.5	–
Turnover	h	233 FIX	–	–
Between-subject variability
EBASE	CV%	28.2	22.8 – 36.6	4
Residual unexplained variability
σprop	CV%	13.8	12.3 – 15.8	12