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. 2022 Jul 20;8:27. doi: 10.1038/s41526-022-00208-5

Table 3.

Overview of the specifications or estimates of the different linear mixed models (LMM).

Fixed effects Estimate (°) Std error (°) CI 95% (°)
Model 1: the effect of long-duration spaceflight on the otolith-mediated reflex, the OCR
Intercept 5.78 0.12 [5.55; 6.02]
Timepoint [BDC2] 0.07 0.16 [−0.24; 0.40]
Timepoint [R + 1/3] −3.76 0.18 [−4.12; −3.40]
Timepoint [R + 4/7] −1.96 0.18 [−2.31; −1.60]
Timepoint [R + 8/12] 0.09 0.16 [−0.22; 0.41]
Orientation [CW] −0.15 0.04 [−0.23; −0.07]
Flight 0.14 0.06 [0.01; 0.26]
Eye_Rotation [Outer Eye] −0.49 0.04 [−0.57; −0.41]
Timepoint [BDC2]*Flight −0.07 0.08 [−0.21; 0.11]
Timepoint [R + 1/3]*Flight 0.50 0.09 [0.32; 0.67]
Timepoint [R + 4/7]*Flight 0.12 0.09 [−0.07; 0.31]
Timepoint [R + 8/12]*Flight −0.07 0.08 [−0.23; 0.09]
Model 2: the OCR re-adapts to the normal gravitational level of Earth
Intercept −0.26 0.38 [−1.01; 0.48]
Flight 1.03 0.15 [0.75; 1.32]
Orientation [CW] −0.23 0.07 [−0.38; −0.09]
Eye_Rotation [Outer Eye] −0.41 0.07 [−0.56; −0.27]
DaysAfterReturn 0.80 0.09 [0.63; 0.97]
DaysAfterReturn*Flight −0.14 0.03 [−0.21; −0.07]
Model 3: the effect of previous spaceflight on the otolith-mediated OCR changes
Intercept 0.18 0.05 [0.09; 0.28]
Flight 0.19 0.03 [0.14; 0.25]
Flight >2 −0.16 0.04 [−0.24; −0.08]

BDC1 was taken as the reference value.

BDC baseline data collection, R + X return after X days.