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. 2022 Jul 20;12:288. doi: 10.1038/s41398-022-02065-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Average alcohol consumed (g/kg) during adolescence (P 28–42) in male and female offspring from dams exposed to polyI:C (Dual) or saline (AE). There were no significant differences between groups, except during session 2 (p > 0.05; n = 9–11/group/sex from 4 dams). B Average alcohol consumed (g/kg) in a limited access paradigm across 3 weeks in adult control, MIA, AE, and dual rats. Drinking rates increased across time in all groups (p = 0.05), but Dual offspring drank significantly more alcohol than all other groups during weeks 2 and 3 (p < 0.05; n = 8–11/group/sex from 12 dams). Female rats drank more alcohol than males (p < 0.05).