Table 3.

Validity (AUC, Sensitivity, Specificity) for CircANXA2, Circ0075001 and CircFBXW7to Discriminate AML (n = 66) from Control (n = 54)

	AUC	p	95% C. I	Cut off	Sensitivity	Specificity	PPV	NPV
CircANXA2	0.824	<0.001*	0.746–0.901	>1.87	74.24	88.89	89.1	73.8
Circ0075001	0.855	<0.001*	0.778–0.932	>1.16	83.33	79.63	83.3	79.6
CircFBXW7	0.826	<0.001*	0.755–0.898	≤1.2	75.76	74.07	78.1	71.4

Abbreviations: AUC, area under a curve; p value, probability value; CI, confidence intervals; NPV, negative predictive value; PPV, positive predictive value; *, statistically significant at p ≤ 0.05.