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. 2022 Jun 13;109(7):1308–1316. doi: 10.1016/j.ajhg.2022.05.011

Figure 2.

Figure 2

Summary of gene panel association tests across binary traits for carriers of likely deleterious variants

Associations are shown for individuals carrying deletions or duplications overlapping 69 known DD loci or rare (n ≤ 5) LoF, missense (REVEL > 0.7), or synonymous variants in any of 599 known monoallelic DDG2P genes compared with the remaining unrelated White Europeans in UKB. 95% confidence intervals shown; unbroken lines, below Bonferroni-corrected p value; dashed lines, above Bonferroni-corrected p value.