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. 2022 Jul 7;109(7):1272–1285. doi: 10.1016/j.ajhg.2022.05.015

Table 1.

Genome-wide genetic correlations between uterine leiomyoma and breast cancer using constrained and unconstrained LDSC

Trait 1 Trait 2 Constrained LDSC
 Unconstrained LDSC
rg rg_SE p rg rg_SE p
Uterine leiomyoma Breast cancer overall 0.09 0.03 6.00 × 10−3 0.07 0.04 5.01 × 10−2
Uterine leiomyoma ER+ breast cancer 0.06 0.03 1.00 × 10−2 0.04 0.04 0.35
Uterine leiomyoma ER– breast cancer 0.06 0.04 0.08 0.05 0.05 0.28

rg, genetic correlation; SE, standard error; ER, estrogen receptor.