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. 2022 Jul 7;16:910662. doi: 10.3389/fncel.2022.910662

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Copyright © 2022 Guerra Leal, Barros-Barbosa, Ferreirinha, Chaves, Rangel, Santos, Carvalho, Martins-Ferreira, Samões, Freitas, Lopes, Ramalheira, Lobo, Martins da Silva, Costa and Correia-de-Sá.

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The P2X7R mRNA is overexpressed in the hippocampus and temporal neocortex of drug-refractory MTLE-HS patients submitted to amygdalohippocampectomy compared to non-epileptic cadaveric controls (CTR). qPCR data are expressed as mean ± SD; n numbers inside each bar represent the number of individuals among 10 controls and 23 MTLE-HS patients in which quality assessment of retrieved RNA samples was suitable for quantification. ^*p < 0.05 (two-way ANOVA followed by Holm-Šídák’s multiple comparisons test was used) represents significant differences when compared to control individuals.