Table 3.
Univariate analysis of explanatory factors for American Joint Committee on Cancer staging
| Characteristic | Stage I | Stage II | Stage III | Stage IV | Overall | P-value |
|---|---|---|---|---|---|---|
| Total (mean n (% by row)) | 126 (24.0) | 68 (12.9) | 109 (20.7) | 223 (42.4) | 526 (100) | |
| Demographic information | ||||||
| – Male sex (mean n (% by column) | 90 (71.4) | 44 (64.7) | 82 (75.2) | 152 (68.2) | 368 (70.0) | 0.647* |
| – Age (mean (SD); years) | 62.2 (10.4) | 64.9 (13.4) | 65.1 (13.4) | 66.5 (11.3) | 65.0 (12) | <0.01† |
| – Median Eastern Cooperative Oncology Group performance status (median (IQR)) | 0 (0–1) | 0 (0–1) | 1 (0–2) | 1 (0–2) | 1 (0–2) | <0.01‡ |
| – Median Scottish Index of Multiple Deprivation (median (IQR)) | 2 (1–4) | 2 (1–3) | 2 (1–4) | 2 (1–3) | 2 (1–3) | 0.137‡ |
| Risk factors (mean n (% by column)) | ||||||
| – Alcohol excess | 31 (24.6) | 15 (22.1) | 34 (31.2) | 96 (43) | 176 (33.5) | <0.001* |
| – Smoking history | 82 (65.1) | 44 (64.7) | 81 (74.3) | 184 (82.5) | 391 (74.3) | <0.001* |
| Cancer subsite (mean n (% by row)) | ||||||
| – Oral | 34 (23.3) | 19 (13.0) | 21 (14.4) | 72 (49.3) | 146 (100) | 0.212* |
| – Larynx | 31 (25.0) | 14 (11.3) | 35 (28.2) | 44 (35.5) | 124 (100) | 0.290* |
| – Cancer of unknown primary | 0 (0.0) | 0 (0.0) | 3 (16.7) | 15 (83.3) | 18 (100) | <0.001* |
*Mann–Whitney U testing; †Spearman's correlation testing; ‡ Kruskal–Wallis H testing. IQR = interquartile range