TABLE 1.

Targeted pathways in AP.

Targeted pathways	Influence	Function	References
Nrf2 pathway	up-regulation	antioxidant	(31)
NF-κB, P38MAPK pathways	up-regulation	Inflammation	(26)
ATF6/p53/AIFM2 pathway	up-regulation	Apoptosis and injury	(29)
TLR signaling pathway	up-regulation	Inflammation; apoptosis	(26, 27)
NLRP3 inflammasome pathway	up-regulation	Inflammation; Pyroptosis	(20, 27, 28)
VCAM-1 and the E-selectin regulation pathway	up-regulation	oxidative stress	(30)
STAT pathway	up-regulation	inflammation	(32, 33)