Table 4.

Comparison of MBL, C3a and cytokines levels in patient with CHIKV infection and healthy controls in acute and chronic phases n = 83

Mediator	CHIKV patients		P value* AP vs. CP	Healthy controls (HC) Median (IQR) pg/µL	P value** CHIKV patients (AP) vs. HC
	Acute phase (AP) Median (IQR) pg/µL	Chronic phase (CP) Median (IQR) pg/µL
MBL	2.3 (1.1-3.8)	1.7 (0.9-3.1)	0.013	1.7 (1.0-2.2)	0.281
C3a	71.1 (65.9-218.9)	72.0 (65.5-198.6)	0.203	147.0 (129.1-184.4)	0.110
IFN-γ	65.0 (31.0-143.7)	54.8 (24.2-123.2)	0.091	9.7 (0.0-38.3)	0.003
TNF-α	11.4 (1.9-26.5)	13.1 (2.9-28.9)	0.930	0.0 (0.0-58.8)	0.119
IL-6	25.8 (0.34-58.3)	22.2 (4.9-52.9)	0.533	0.0 (0.0-0.4)	< 0.001
IL-12	1.6 (0.0-6.1)	2.5 (0.0-14.1)	0.096	0.0 (0.0-7.6)	0.089
IL-10	28.6 (14.7-51.4)	17.1 (10.4-26.1)	< 0.001	7.7 (5.5-10.5)	< 0.001
IL-8	74.4 (23.8-264.9)	44.5 (14.7-317.1)	0.882	7.8 (4.9-23.9)	< 0.001
MIP-1	21.6 (5.3-50.1)	9.5 (0.0-25.4)	0.004	0.0 (0.0-1.6)	< 0.001
MCP-1	197.9 (132.3-325.5)	197.7 (119.9-305)	0.172	135.1 (61.9-272.1)	0.114
RANTES	5201.4 (4480.7-10478.9)	5390.8 (4734-8451.4)	0.499	6973.1 (2426.3-13174.9)	0.926
GS-CSF	0.00 (0.00-0.901)	0.00 (0.00-1.39)	0.375	0.00 (0.00-0.48)	0.510

^*Wilcoxon test;

^**Mann-Whitney test.